NOTES ON HIBERNATING MAMMALS

Notes on Cortical Areas in Mammals

The past two centuries of work on the structure and function of the cerebral cortex have been characterized by recurring debates—often too often forgotten and re-argued—involving several basic oppositions. Two of these are: (1) "field" versus "localization" theories of cortical function, and (2) higher-level, abstract (linguistic) facilities versus lower-level, less abstract, sensorimotor funct...

Genes controlling the metabolic switch in hibernating mammals.

Hibernating mammals have the ability to decrease their metabolic rate and survive up to 6 months without food in an inactive state where body temperatures approach 0 degrees C. In hibernating 13-lined ground squirrels (Spermophilus tridecemlineatus), oxygen consumption holds at 1/30 to 1/50 of the aroused condition and heart rates are as low as 3-10 beats/min, compared with 200-300 beats/min wh...

Endocrine regulation of bone and energy metabolism in hibernating mammals.

Precise coordination among organs is required to maintain homeostasis throughout hibernation. This is particularly true in balancing bone remodeling processes (bone formation and resorption) in hibernators experiencing nutritional deprivation and extreme physical inactivity, two factors normally leading to pronounced bone loss in non-hibernating mammals. In recent years, important relationships...

A Recording Cardiotachometer for Radio Capsules Implanted in Mammals With Data From Hibernating Mammals

Repeated functional convergent effects of NaV1.7 on acid insensitivity in hibernating mammals.

Hibernating mammals need to be insensitive to acid in order to cope with conditions of high CO2; however, the molecular basis of acid tolerance remains largely unknown. The African naked mole-rat (Heterocephalus glaber) and hibernating mammals share similar environments and physiological features. In the naked mole-rat, acid insensitivity has been shown to be conferred by the functional motif o...